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Sue's doctoral research led to a number of publications about influences of variable number tandem repeats (VNTRs) in proteins associated with the cell surface [1-4].
In postdoctoral research she has investigated the role of double strand breaks in meiosis and various DNA repair pathways. She also researched evolution of metal binding in prion protein VNTRs .
Her most recent research used publicly available datasets to investigate consequences of VNTR stability in human protein interactions .
5. Klewpatinond M, Davies P, Bowen S, Brown DR, Viles JH. De-convoluting the Cu(II) binding modes of full-length prion protein. J. Biol. Chem. 2008;283:1870-1881.
6. Bowen S. Protein function influences frequency of encoded regions containing VNTRs and number of unique interactions. 2012;arXiv:1209.5760 [q-bio.GN]
Sue currently works freelance as a fully trained STM copy editor. She is a highly qualified scientist who has created, written and published her own research. She also designs and maintains a number of weblogs and online sites (including this one).
Before becoming a scientist, Sue trained as a commercial artist and photographer. She worked mainly in-house, producing camera-ready copy and typesetting for publishers, institutions and commercial printers. Amongst her clients were the National Museum of Wales, National Union of Students, Allied Steel and Wire (ASW), British Telecom and Glamorgan County Cricket Club.
1. Bowen S, Roberts C, Wheals AE. Patterns of polymorphism and divergence in stress-related yeast proteins. Yeast. 2005;22:659-668.
2. Mannazzu I, Simonetti E, Marinangeli P, Guerra E, Budroni M, Thangavelu M, Bowen S, Wheals AE, Clementi F. SED1 gene length and sequence polymorphisms in feral strains of Saccharomyces cerevisiae. Appl. Environ. Microbiol. 2002;68(11):5437-5444.
3. Bowen S, Wheals AE. Ser/Thr-rich domains are associated with genetic variation and morphogenesis in Saccharomyces cerevisiae. Yeast. 2006;23:633-640.
4. Bowen S, Wheals AE. Evidence that protein expansion and contraction is partly owing to pre-meiotic mutational events. Mol. Biol. Evol. 2006;23:1339-1340.
Sue Bowen PhD ([email protected])
PhD, University of Bath (2001)
MSc, Universities of Leicester & Nottingham (1997)
BSc (Hons), University of Wales, College Cardiff (1995)
Specialized Fields: Cell biology; Genetics (microbial, lower vertebrate & mammalian); DNA repair systems; Mutation & genetic instability; Cancer management & research; Neurobiology; Protein characterization; Evolution; Signal transduction; Bioinformatics.